Is Cetirizine Safe with Quercetin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Use with caution. Inform your doctor if taking quercetin supplements alongside cetirizine. Watch for increased side effects such as sedation or dry mouth.
Why this interaction occurs
Quercetin has demonstrated inhibition of renal organic anion transporters (OATs), which are involved in cetirizine elimination. Reduced renal clearance of cetirizine may lead to elevated drug concentrations and amplified antihistaminic side effects.
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 1,497 reports mentioning Quercetin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Quercetin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Cetirizine interactions → · All Quercetin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.