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Is Cottonseed Meal Safe with levothyroxine?

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levothyroxine Cottonseed Meal
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Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature

WHAT YOU NEED TO KNOW

Avoid consuming cottonseed meal close to your levothyroxine dose; dosage adjustments may be necessary.

Why this interaction occurs

Cottonseed meal may bind levothyroxine in the gastrointestinal tract and decrease its absorption.

Evidence

Evidence level: strong.

Data source

FDA Drug Label

Reported safety data

The FDA’s adverse event reporting system (FAERS) has received 302,514 reports mentioning levothyroxine. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the levothyroxine + supplement combination on this page.

FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.

Frequently asked questions

Can I take Cottonseed Meal with levothyroxine?
Avoid consuming cottonseed meal close to your levothyroxine dose; dosage adjustments may be necessary.
Does Cottonseed Meal affect how well levothyroxine works?
Cottonseed meal may bind levothyroxine in the gastrointestinal tract and decrease its absorption.

Related interactions

Soybean flour / Soy and levothyroxine Walnuts and levothyroxine Dietary Fiber and levothyroxine Grapefruit Juice and levothyroxine Slow-Release Nicotinic Acid (Niacin) and levothyroxine Soybean / Soy Flour and levothyroxine

All Cottonseed Meal interactions →  ·  All levothyroxine interactions →

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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.