Is cranberry juice / cranberry supplements Safe with cyclosporine?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Moderate consumption of cranberry juice appears safe with cyclosporine based on current evidence, but avoid large quantities (1–2 L/day) or concentrated cranberry supplements. Report any unusual symptoms to your physician.
Why this interaction occurs
However, in vivo studies with cyclosporine specifically have not confirmed a clinically significant pharmacokinetic interaction, possibly due to limited bioavailability of active anthocyanins.
Evidence
Evidence level: limited.
Data source
PubMed - PMID 23958198
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 58,058 reports mentioning cyclosporine. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the cyclosporine + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All cranberry juice / cranberry supplements interactions → · All cyclosporine interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.