Is Garlic Extract Safe with Isoflurane?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid combining Garlic Extract with Isoflurane — Garlic Extract blocks the liver enzyme (CYP2E1) that processes Isoflurane, potentially raising Isoflurane levels to toxic range. Consult your doctor or pharmacist.
Why this interaction occurs
Diallyl sulfide inhibits CYP2E1.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 2,008 reports mentioning Isoflurane. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Isoflurane + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Garlic Extract interactions → · All Isoflurane interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.