Is Iron (Ferrous Sulfate) Safe with Pea Protein?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Take iron supplements at least 2 hours apart from pea protein shakes. Patients on erythropoiesis-stimulating agents (ESAs) for CKD-related anemia should be particularly vigilant about iron absorption.
Why this interaction occurs
Pea protein contains phytates which chelate non-heme iron and significantly reduce its intestinal absorption. Patients with CKD-associated anemia dependent on adequate iron stores for ESA efficacy may experience suboptimal treatment response.
Evidence
Evidence level: strong.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 764,244 reports mentioning Pea Protein. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Pea Protein + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Iron (Ferrous Sulfate) interactions → · All Pea Protein interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.