Is Magnesium (oral supplements) Safe with Modified Citrus Pectin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Separate magnesium supplementation from modified citrus pectin by at least 2 hours. Monitor for signs of magnesium deficiency with long-term concurrent use.
Why this interaction occurs
Soluble fibers including pectin bind magnesium in the GI tract via ionic interactions. Modified citrus pectin's high uronic acid content facilitates chelation of Mg²⁺, reducing net intestinal magnesium absorption.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 90,141 reports mentioning Modified Citrus Pectin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Modified Citrus Pectin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Magnesium (oral supplements) interactions → · All Modified Citrus Pectin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.