Is Vitamin K (oral supplements) Safe with Chlorophyll?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Monitor INR and vitamin K status closely.
Why this interaction occurs
Chlorophyll is structurally related to phytol chains associated with phylloquinone (vitamin K1). High-dose liquid or supplement chlorophyll can contribute meaningful amounts of vitamin K1 activity, which may interact with supplemental vitamin K dosing or anticoagulation therapy, creating unpredictable vitamin K effects.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 291 reports mentioning Chlorophyll. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Chlorophyll + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Vitamin K (oral supplements) interactions → · All Chlorophyll interactions →
Already checked this one — check your whole list
Educational only — not medical advice.
Always confirm with your doctor or pharmacist.