Is Botanical (Herbal) Products (general) Safe with warfarin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Tell your doctor about all herbal and botanical supplements you take. More frequent INR monitoring is required when starting or stopping any botanical product.
Why this interaction occurs
The FDA label explicitly warns that botanical and herbal products can interact with warfarin through pharmacodynamic or pharmacokinetic mechanisms, requiring more frequent INR monitoring when starting or stopping their use.
Evidence
Evidence level: strong.
Data source
FDA Drug Label (OpenFDA)
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 134,328 reports mentioning warfarin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the warfarin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Botanical (Herbal) Products (general) interactions → · All warfarin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.