Is Coenzyme Q10 (CoQ10) Safe with Benazepril?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
CoQ10 (100–200 mg/day) may be used adjunctively but patients should monitor blood pressure regularly, as combined use may produce additive blood pressure lowering. Adjust antihypertensive therapy if needed under physician supervision.
Why this interaction occurs
CoQ10 has demonstrated mild antihypertensive properties in clinical trials. When combined with Benazepril, there is a potential for additive blood pressure reduction. While generally beneficial, this combination warrants monitoring to avoid excessive hypotension, especially in elderly patients.
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 20,900 reports mentioning Benazepril. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Benazepril + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Coenzyme Q10 (CoQ10) interactions → · All Benazepril interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.