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Is Curcumin Safe with Celecoxib?

⚠️ HIGH SEVERITY
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Celecoxib Curcumin
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Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature

WHAT YOU NEED TO KNOW

Avoid combining Curcumin with Celecoxib — Curcumin blocks the liver enzyme (CYP2C9) that processes Celecoxib, potentially raising Celecoxib levels to toxic range. Consult your doctor or pharmacist.

Evidence

Evidence level: moderate.

Reported safety data

The FDA’s adverse event reporting system (FAERS) has received 37,331 reports mentioning Celecoxib. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Celecoxib + supplement combination on this page.

FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.

Frequently asked questions

Can I take Curcumin with Celecoxib?
Avoid unless your doctor or pharmacist directs otherwise. Avoid combining Curcumin with Celecoxib — Curcumin blocks the liver enzyme (CYP2C9) that processes Celecoxib, potentially raising Celecoxib levels to toxic range. Consult your doctor or pharmacist.

Related interactions

Ginkgo biloba and Celecoxib Fish Oil and Celecoxib Turmeric and Celecoxib St. John's Wort and Celecoxib Milk Thistle and Celecoxib

All Curcumin interactions →  ·  All Celecoxib interactions →

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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.