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Is Curcumin Safe with Fluvoxamine?

⚠️ HIGH SEVERITY
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Fluvoxamine Curcumin
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Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature

WHAT YOU NEED TO KNOW

Avoid combining Curcumin with Fluvoxamine — Curcumin blocks the liver enzyme (CYP2C9) that processes Fluvoxamine, potentially raising Fluvoxamine levels to toxic range. Consult your doctor or pharmacist.

Evidence

Evidence level: moderate.

Reported safety data

The FDA’s adverse event reporting system (FAERS) has received 6,443 reports mentioning Fluvoxamine. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Fluvoxamine + supplement combination on this page.

FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.

Frequently asked questions

Can I take Curcumin with Fluvoxamine?
Avoid unless your doctor or pharmacist directs otherwise. Avoid combining Curcumin with Fluvoxamine — Curcumin blocks the liver enzyme (CYP2C9) that processes Fluvoxamine, potentially raising Fluvoxamine levels to toxic range. Consult your doctor or pharmacist.

Related interactions

St. John's Wort and Fluvoxamine Milk Thistle and Fluvoxamine Echinacea and Fluvoxamine Ginkgo Biloba and Fluvoxamine Melatonin and Fluvoxamine

All Curcumin interactions →  ·  All Fluvoxamine interactions →

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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.