Is Fish Oil Safe with Dabigatran?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Use fish oil supplements cautiously and only at low doses (<1g/day). Monitor for bleeding symptoms and notify your healthcare provider before starting or stopping fish oil supplementation.
Why this interaction occurs
Fish oil impairs platelet function via reduced thromboxane A2 production. While dabigatran directly inhibits thrombin, the antiplatelet effect of fish oil adds a secondary bleeding mechanism, increasing overall hemorrhagic risk.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 8,321 reports mentioning Dabigatran. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Dabigatran + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Fish Oil interactions → · All Dabigatran interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.