Is Ginkgo Safe with Dabigatran?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Do not combine ginkgo biloba with dabigatran. If you are already using both, contact your healthcare provider immediately. Look for warning signs of bleeding: red or dark urine, bloody stools, unusual bruising, or prolonged bleeding.
Why this interaction occurs
Ginkgo biloba strongly inhibits platelet aggregation through PAF antagonism and may also inhibit P-glycoprotein, potentially increasing dabigatran plasma concentrations since dabigatran is a P-gp substrate. This dual pharmacokinetic and pharmacodynamic interaction creates critical bleeding risk.
Evidence
Evidence level: strong.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 8,321 reports mentioning Dabigatran. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Dabigatran + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Ginkgo interactions → · All Dabigatran interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.