Is Ginkgo biloba Safe with NSAIDs (general)?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid concurrent use of Ginkgo biloba with NSAIDs. If both are required, use the lowest effective NSAID dose for the shortest duration and monitor for gastrointestinal or systemic bleeding. Report any unusual bruising or bleeding to your provider.
Why this interaction occurs
NSAIDs inhibit platelet aggregation via COX-1 inhibition; combined with Ginkgo biloba's antiplatelet effects, this creates an additive risk of bleeding and coagulation abnormalities.
Evidence
Evidence level: moderate.
Data source
PubMed - PMID 42081645
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 1,274,591 reports mentioning NSAIDs (general). This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the NSAIDs (general) + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Ginkgo biloba interactions → · All NSAIDs (general) interactions →
Already checked this one — check your whole list
Educational only — not medical advice.
Always confirm with your doctor or pharmacist.