Is Ginkgo biloba Safe with Clopidogrel?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid combining Ginkgo biloba with clopidogrel. If use cannot be avoided, monitor closely for signs of bleeding (unusual bruising, prolonged bleeding, blood in urine/stool). Inform your prescriber of all supplements taken.
Why this interaction occurs
Ginkgo biloba has antiplatelet properties that may be additive or synergistic with clopidogrel's antiplatelet mechanism, significantly increasing bleeding risk and causing abnormal coagulation profiles.
Evidence
Evidence level: strong.
Data source
PubMed - PMID 40198642
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 108,615 reports mentioning Clopidogrel. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Clopidogrel + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Ginkgo biloba interactions → · All Clopidogrel interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.