Is Magnesium Safe with Carvedilol?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Do not take high-dose magnesium supplements without consulting your physician. Seek immediate care if you experience slow heartbeat, severe dizziness, or fainting.
Why this interaction occurs
Carvedilol has both beta-blocking and alpha-blocking properties. Magnesium's vasodilatory and cardiac conduction-slowing effects can compound Carvedilol's effects, increasing the risk of clinically significant hypotension and bradycardia.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 102,493 reports mentioning Carvedilol. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Carvedilol + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Magnesium interactions → · All Carvedilol interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.