Is Alcohol Safe with quetiapine?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Limit or avoid alcoholic beverages while taking quetiapine. Even moderate alcohol consumption can worsen cognitive and motor impairment caused by quetiapine.
Why this interaction occurs
The FDA label states that quetiapine potentiated the cognitive and motor effects of alcohol in a clinical trial in subjects with selected psychotic disorders. As a centrally acting substance, alcohol combined with quetiapine increases CNS depression beyond what either substance causes alone.
Evidence
Evidence level: strong.
Data source
FDA Drug Label
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 111,480 reports mentioning quetiapine. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the quetiapine + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Alcohol interactions → · All quetiapine interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.