Is Alcohol Safe with mirtazapine?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid consuming alcohol while taking mirtazapine, as it significantly worsens cognitive and motor impairment caused by mirtazapine alone.
Why this interaction occurs
Concomitant use of alcohol with mirtazapine increases the impairment of cognitive and motor skills produced by mirtazapine alone.
Evidence
Evidence level: strong.
Data source
FDA Drug Label
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 77,936 reports mentioning mirtazapine. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the mirtazapine + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Alcohol interactions → · All mirtazapine interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.