Is Food (general) Safe with isoniazid?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Take isoniazid on an empty stomach. Do not administer with food.
Why this interaction occurs
Studies have shown that the bioavailability of isoniazid is reduced significantly when administered with food.
Evidence
Evidence level: strong.
Data source
FDA Drug Label
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 17,281 reports mentioning isoniazid. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the isoniazid + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Food (general) interactions → · All isoniazid interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.