Is Tyramine-containing foods (cheese, red wine) Safe with isoniazid?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid tyramine-containing foods such as aged cheese and red wine while taking isoniazid.
Why this interaction occurs
Isoniazid has monoamine oxidase inhibiting activity, which can cause an interaction with tyramine-containing foods, potentially leading to hypertensive or adverse reactions.
Evidence
Evidence level: strong.
Data source
FDA Drug Label
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 17,281 reports mentioning isoniazid. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the isoniazid + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Tyramine-containing foods (cheese, red wine) interactions → · All isoniazid interactions →
Already checked this one — check your whole list
Educational only — not medical advice.
Always confirm with your doctor or pharmacist.