Is Hawthorn Safe with Warfarin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Inform your anticoagulation clinic if you are taking Hawthorn. Do not start, stop, or change the dose without medical guidance. Increase INR monitoring frequency.
Why this interaction occurs
Hawthorn may potentiate the anticoagulant effects of warfarin, potentially by inhibiting platelet aggregation and altering drug metabolism via CYP450 pathways. This interaction has been reported to elevate INR and increase bleeding risk.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 134,328 reports mentioning Warfarin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Warfarin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Hawthorn interactions → · All Warfarin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.