Is Magnesium Safe with Adderall?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Take magnesium at least 2 hours apart from Adderall. Do not exceed 350mg elemental magnesium daily without physician guidance.
Why this interaction occurs
High-dose magnesium may also reduce GI absorption of amphetamines when taken simultaneously.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 46,784 reports mentioning Adderall. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Adderall + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Magnesium interactions → · All Adderall interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.