Is Meals high in bran (dietary fiber) Safe with digoxin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Measure serum digoxin concentrations if dietary habits change significantly. Continue monitoring and increase digoxin dose by approximately 20% to 40% as necessary under medical supervision.
Why this interaction occurs
Meals high in bran are listed as agents that decrease digoxin concentrations, likely by reducing gastrointestinal absorption of digoxin, which may lead to subtherapeutic drug levels.
Evidence
Evidence level: strong.
Data source
FDA Drug Label
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 64,171 reports mentioning digoxin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the digoxin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Meals high in bran (dietary fiber) interactions → · All digoxin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.