Is Thyroid supplements Safe with digoxin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Inform your doctor if you are taking any thyroid supplement. Digoxin levels should be monitored closely as your thyroid hormone levels are treated, since dose adjustments may be needed.
Why this interaction occurs
The FDA label notes that treatment of hypothyroidism with thyroid supplements in patients taking digoxin may increase the dose requirements of digoxin.
Evidence
Evidence level: strong.
Data source
FDA Drug Label (OpenFDA)
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 64,171 reports mentioning digoxin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the digoxin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Thyroid supplements interactions → · All digoxin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.