Is Iron Safe with Vyvanse?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Separate Vyvanse and iron dosing by at least 2 hours. Watch for signs of reduced medication effectiveness such as return of inattention or hyperactivity.
Why this interaction occurs
The interaction is considered less pronounced than with immediate-release amphetamines but remains clinically relevant.
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 28,912 reports mentioning Vyvanse. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Vyvanse + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Iron interactions → · All Vyvanse interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.