Is Bilberry Safe with Warfarin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid combining bilberry supplements with warfarin. If already taking both, inform your healthcare provider immediately and monitor INR levels more frequently. Do not stop either without medical guidance.
Why this interaction occurs
Bilberry contains anthocyanosides that inhibit platelet aggregation and may have additive anticoagulant effects when combined with warfarin, potentially increasing the risk of bleeding. Bilberry may also inhibit thromboxane synthesis, further potentiating anticoagulant activity.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 134,328 reports mentioning Warfarin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Warfarin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Bilberry interactions → · All Warfarin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.