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Is Bilberry Safe with Aspirin?

ℹ️ MODERATE SEVERITY
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Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature

WHAT YOU NEED TO KNOW

Use caution when combining bilberry with aspirin, especially at higher doses. Watch for signs of unusual bruising or prolonged bleeding. Consult your pharmacist or physician before starting bilberry supplements.

Why this interaction occurs

Both bilberry anthocyanosides and aspirin inhibit platelet aggregation through complementary mechanisms. Concurrent use may produce an additive antiplatelet effect, increasing the risk of bleeding particularly in patients on high-dose aspirin therapy.

Evidence

Evidence level: moderate.

Reported safety data

The FDA’s adverse event reporting system (FAERS) has received 617,935 reports mentioning Aspirin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Aspirin + supplement combination on this page.

FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.

Frequently asked questions

Can I take Bilberry with Aspirin?
Use caution when combining bilberry with aspirin, especially at higher doses. Watch for signs of unusual bruising or prolonged bleeding. Consult your pharmacist or physician before starting bilberry supplements.
How long should I wait between Aspirin and Bilberry?
Use caution when combining bilberry with aspirin, especially at higher doses. Watch for signs of unusual bruising or prolonged bleeding. Consult your pharmacist or physician before starting bilberry supplements.

Related interactions

All Bilberry interactions →  ·  All Aspirin interactions →

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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.