Is Bilberry Safe with Clopidogrel?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Inform your cardiologist or prescriber before taking bilberry supplements while on clopidogrel. Monitor for signs of bleeding such as unusual bruising, blood in urine or stools, or prolonged bleeding from cuts.
Why this interaction occurs
Bilberry's anthocyanosides exhibit antiplatelet properties that may additively enhance the platelet inhibition caused by clopidogrel, increasing bleeding risk. This combination warrants clinical monitoring especially in high cardiovascular risk patients.
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 108,615 reports mentioning Clopidogrel. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Clopidogrel + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Bilberry interactions → · All Clopidogrel interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.