Is Boswellia Safe with Warfarin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Use caution and monitor INR frequently if combining these agents. Inform your anticoagulation clinic of any Boswellia supplement use. Avoid initiating or stopping Boswellia without adjusting warfarin monitoring.
Why this interaction occurs
Boswellic acids inhibit CYP2C9, the primary enzyme responsible for warfarin (S-warfarin) metabolism. CYP2C9 inhibition can reduce warfarin clearance, elevating plasma levels and increasing bleeding risk.
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 134,328 reports mentioning Warfarin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Warfarin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Boswellia interactions → · All Warfarin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.