Is DHA (Docosahexaenoic Acid) Safe with Warfarin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Discuss with your prescriber before use. Frequent INR monitoring is recommended. Avoid high-dose DHA supplementation without medical guidance.
Why this interaction occurs
DHA reduces platelet aggregation and thromboxane A2 production, which can potentiate warfarin's anticoagulant effect and increase bleeding risk.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 134,328 reports mentioning Warfarin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Warfarin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All DHA (Docosahexaenoic Acid) interactions → · All Warfarin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.