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Is Ginkgo Biloba Safe with Glyburide?

ℹ️ MODERATE SEVERITY
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Glyburide Ginkgo Biloba
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Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature

WHAT YOU NEED TO KNOW

Avoid combining Ginkgo Biloba with Glyburide — Ginkgo Biloba speeds up the liver enzyme (CYP2C9) that breaks down Glyburide, potentially reducing its effectiveness. Consult your doctor.

Why this interaction occurs

Ginkgo induces CYP2C9 reducing drug levels. Result: decreased drug levels.

Evidence

Evidence level: moderate.

Reported safety data

The FDA’s adverse event reporting system (FAERS) has received 26,393 reports mentioning Glyburide. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Glyburide + supplement combination on this page.

FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.

Frequently asked questions

Can I take Ginkgo Biloba with Glyburide?
Avoid combining Ginkgo Biloba with Glyburide — Ginkgo Biloba speeds up the liver enzyme (CYP2C9) that breaks down Glyburide, potentially reducing its effectiveness. Consult your doctor.

Related interactions

St. John's Wort and Glyburide Milk Thistle and Glyburide Curcumin and Glyburide Ginkgo Biloba and Apixaban Ginkgo Biloba and Rivaroxaban Ginkgo Biloba and Warfarin Ginkgo Biloba and Acenocoumarol Ginkgo Biloba and Phenytoin

All Ginkgo Biloba interactions →  ·  All Glyburide interactions →

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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.