Is Ginkgo Biloba Safe with Warfarin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid this combination. If use is unavoidable, report any unusual bruising, prolonged bleeding, blood in urine or stool immediately. Ensure frequent INR monitoring and inform your anticoagulation clinic.
Why this interaction occurs
Ginkgo biloba inhibits platelet-activating factor (PAF) and has intrinsic antiplatelet properties. Combined with warfarin, this produces additive anticoagulant effects, increasing the risk of serious bleeding including intracranial hemorrhage.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 134,328 reports mentioning Warfarin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Warfarin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Ginkgo Biloba interactions → · All Warfarin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.