Is Ginkgo Biloba Safe with Rivaroxaban?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid ginkgo biloba entirely while on rivaroxaban. This is considered a contraindicated combination. Immediately inform your prescriber if you are using ginkgo. Do not self-discontinue rivaroxaban without medical guidance.
Why this interaction occurs
Ginkgolides A and B in ginkgo biloba are potent PAF antagonists that impair platelet function. This pharmacodynamic interaction with rivaroxaban's anticoagulation significantly increases risk of major bleeding events including GI bleeds and intracranial hemorrhage.
Evidence
Evidence level: strong.
Data source
PubMed: PMID 35517810
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 28,402 reports mentioning Rivaroxaban. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Rivaroxaban + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Ginkgo Biloba interactions → · All Rivaroxaban interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.