Is Turmeric Safe with Ibuprofen?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Use caution when combining turmeric supplements (curcumin) with ibuprofen. Limit turmeric to culinary amounts if possible. Watch for signs of GI upset or unusual bleeding and inform your healthcare provider.
Why this interaction occurs
Curcumin, the active compound in turmeric, inhibits platelet aggregation and has anticoagulant properties. Combined with ibuprofen's COX-1-mediated platelet inhibition and GI mucosal effects, the combination raises bleeding and GI complication risk.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 218,701 reports mentioning Ibuprofen. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Ibuprofen + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Turmeric interactions → · All Ibuprofen interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.