Is Astaxanthin Safe with Rivaroxaban?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Discuss with your physician before combining. Watch for signs of bleeding including dark stools, excessive bruising, or prolonged wound bleeding.
Why this interaction occurs
Similar to other DOACs, rivaroxaban combined with astaxanthin's antiplatelet and possible P-glycoprotein modulating properties may enhance net anticoagulant effect. Preclinical data suggests astaxanthin may influence drug transporter activity affecting DOAC bioavailability.
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 28,402 reports mentioning Rivaroxaban. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Rivaroxaban + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Astaxanthin interactions → · All Rivaroxaban interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.