Is Turmeric Safe with Rivaroxaban?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid curcumin or turmeric supplements while taking rivaroxaban. Use only dietary amounts in cooking. Discuss any supplement use with your pharmacist or physician before starting.
Why this interaction occurs
Curcumin may inhibit P-glycoprotein (P-gp), a key efflux transporter for rivaroxaban, potentially increasing rivaroxaban plasma levels. Combined with curcumin's intrinsic antiplatelet and anticoagulant activity, the interaction can meaningfully increase hemorrhagic risk.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 28,402 reports mentioning Rivaroxaban. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Rivaroxaban + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Turmeric interactions → · All Rivaroxaban interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.