Is Astaxanthin Safe with Apixaban?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Use caution. Report any unusual bleeding, prolonged bruising, or blood in urine/stool to your healthcare provider immediately.
Why this interaction occurs
Astaxanthin exhibits antiplatelet activity through inhibition of thromboxane B2 and platelet aggregation. When combined with direct oral anticoagulants like apixaban, this additive effect on hemostasis may increase clinically significant bleeding risk.
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 67,478 reports mentioning Apixaban. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Apixaban + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Astaxanthin interactions → · All Apixaban interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.