Is Chaga (Inonotus obliquus) Safe with Aspirin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Inform your doctor if you are taking Chaga with aspirin, especially at higher doses. Be alert for signs of unusual bleeding and avoid this combination before any surgical procedure.
Why this interaction occurs
Chaga contains betulinic acid and other compounds with antiplatelet activity. Combined with aspirin's cyclooxygenase inhibition, this creates an additive antiplatelet effect that may increase bleeding risk, particularly in patients with cardiovascular disease on dual therapy.
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 617,935 reports mentioning Aspirin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Aspirin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Chaga (Inonotus obliquus) interactions → · All Aspirin interactions →
Already checked this one — check your whole list
Educational only — not medical advice.
Always confirm with your doctor or pharmacist.