Is Ginkgo Biloba Safe with Fluconazole?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Use caution combining Ginkgo Biloba with Fluconazole. Ginkgo Biloba may mildly speed up Fluconazole metabolism via CYP3A4. Monitor for reduced effectiveness.
Why this interaction occurs
Weak CYP3A4 induction. Result: slightly decreased drug levels. Low clinical risk
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 58,684 reports mentioning Fluconazole. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Fluconazole + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Ginkgo Biloba interactions → · All Fluconazole interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.