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Is Ginkgo Biloba Safe with Ibuprofen?

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Ibuprofen Ginkgo Biloba
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Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature

WHAT YOU NEED TO KNOW

Avoid combining Ginkgo Biloba with Ibuprofen — Ginkgo Biloba speeds up the liver enzyme (CYP2C9) that breaks down Ibuprofen, potentially reducing its effectiveness. Consult your doctor.

Why this interaction occurs

Ginkgo induces CYP2C9 reducing drug levels. Result: decreased drug levels.

Evidence

Evidence level: moderate.

Reported safety data

The FDA’s adverse event reporting system (FAERS) has received 218,701 reports mentioning Ibuprofen. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Ibuprofen + supplement combination on this page.

FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.

Frequently asked questions

Can I take Ginkgo Biloba with Ibuprofen?
Avoid combining Ginkgo Biloba with Ibuprofen — Ginkgo Biloba speeds up the liver enzyme (CYP2C9) that breaks down Ibuprofen, potentially reducing its effectiveness. Consult your doctor.

Related interactions

Fish Oil and Ibuprofen Willow Bark and Ibuprofen Turmeric and Ibuprofen Bromelain and Ibuprofen Devils Claw and Ibuprofen St. John's Wort and Ibuprofen Milk Thistle and Ibuprofen Curcumin and Ibuprofen

All Ginkgo Biloba interactions →  ·  All Ibuprofen interactions →

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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.