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Is Gotu Kola Safe with Warfarin?

ℹ️ MODERATE SEVERITY
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Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature

WHAT YOU NEED TO KNOW

Monitor INR more frequently if starting or stopping Gotu Kola. Do not make changes without informing your anticoagulation clinic or prescriber.

Why this interaction occurs

Gotu Kola contains triterpenoids with potential platelet aggregation inhibitory effects. Combined with warfarin, there is a theoretical increased bleeding risk. Hepatotoxic potential of Gotu Kola may also affect hepatic CYP enzymes involved in warfarin metabolism.

Evidence

Evidence level: limited.

Reported safety data

The FDA’s adverse event reporting system (FAERS) has received 134,328 reports mentioning Warfarin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Warfarin + supplement combination on this page.

FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.

Frequently asked questions

Can I take Gotu Kola with Warfarin?
Monitor INR more frequently if starting or stopping Gotu Kola. Do not make changes without informing your anticoagulation clinic or prescriber.

Related interactions

All Gotu Kola interactions →  ·  All Warfarin interactions →

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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.