Is Turmeric Safe with Apixaban?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Avoid turmeric supplements or curcumin extracts while on apixaban. Culinary use in small amounts is generally acceptable. Watch for signs of bleeding and inform your prescriber of any supplement use.
Why this interaction occurs
Curcumin, the active compound in turmeric, inhibits platelet aggregation by suppressing thromboxane B2 and platelet-activating factor. It also demonstrates anticoagulant properties by inhibiting tissue factor and reducing fibrinogen. These mechanisms potentiate apixaban's anticoagulant effect and increase bleeding risk.
Evidence
Evidence level: moderate.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 67,478 reports mentioning Apixaban. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Apixaban + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Turmeric interactions → · All Apixaban interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.