Is White Willow Safe with Warfarin?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Do not use White Willow Bark while taking Warfarin. If you are already using it, inform your doctor immediately and have your INR checked. Watch for unusual bruising, prolonged bleeding, or blood in urine/stool.
Why this interaction occurs
White Willow Bark contains salicin, which is metabolized to salicylic acid — pharmacologically similar to aspirin. It inhibits platelet aggregation and may potentiate Warfarin's anticoagulant effect, significantly elevating INR and hemorrhage risk.
Evidence
Evidence level: strong.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 134,328 reports mentioning Warfarin. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Warfarin + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All White Willow interactions → · All Warfarin interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.