Is Devils Claw Safe with Lisinopril?
Free · No account · based on published sources including NIH ODS, FDA drug labels, and peer-reviewed literature
Monitor blood pressure regularly if using Devil's Claw with antihypertensive medications. Report symptoms of dizziness, lightheadedness, or fainting to your doctor. Dose adjustments may be needed.
Why this interaction occurs
Devil's Claw has demonstrated mild antihypertensive properties in preclinical and limited clinical studies. Combined with ACE inhibitors like Lisinopril, there is a risk of additive hypotensive effects.
Evidence
Evidence level: limited.
Reported safety data
The FDA’s adverse event reporting system (FAERS) has received 323,131 reports mentioning Lisinopril. This reflects reported cases involving the medication in general — not confirmed causation, and not specific to the Lisinopril + supplement combination on this page.
FAERS reports are voluntary and cannot prove that a drug caused an event. Do not use report counts to assess the safety of this specific drug-supplement pair.
Frequently asked questions
Related interactions
All Devils Claw interactions → · All Lisinopril interactions →
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Educational only — not medical advice.
Always confirm with your doctor or pharmacist.